Hypochlorous Acid Water Generator

Summary of hypochlorous Acid (HOCl)

HOCl can be used in many industries, from agriculture, restaurants, food, and healthcare applications, including chronic wound care and disinfection.  Hypochlorous acid water is ideal for disinfection solution, low price, safe, and could be applied in a wide range of areas for sterilization and virus-killing effects.

An ideal disinfectant and sanitiser must be nontoxic to surface contact, non-corrosive, effective in various forms, and relatively inexpensive. HOCl may be the disinfectant of choice for coronaviruses in an oral-maxillofacial surgery (OMS) office.

HOCl is an endogenous substance in all mammals and is effective against a broad range of microorganisms. Neutrophils, eosinophils, mononuclear phagocytes, and B lymphocytes produce HOCl in response to injury and infection through the mitochondrial membrane-bound enzyme known as “respiratory burst nicotinamide adenine dinucleotide phosphate oxidase.”   HOCl selectively binds with the unsaturated lipid layer and subsequently disrupts cellular integrity. Between pH levels of 3 and 6, the predominant species is HOCl that has maximal antimicrobial properties.

HOCl is a powerful oxidizing agent. In an aqueous solution, it dissociates into H⁺ and OCl^–, denaturing and aggregating proteins.  HOCl also destroys viruses by chlorination by forming chloramines and nitrogen-centred radicals, resulting in single- as well as double-stranded DNA breaks, rendering the nucleic acid useless and the virus harmless.

How Is HOCl Made?
It is made through an electrolysis processing machine and the ingredients are soft water and salt. Fill in the container with 5000 c.c. of soft water, and 50g salts. After stirring, put it into the electrolysis equipment. Press the designated button on the instrument. The electrolyte will be completed within 30 minutes. After the electrolyte is complete, please let the machine rest for 20 minutes before it can be used again. 

How to kill bacteria?
The principle of hypochlorous acid water sterilization is to inhibit the activity of germs by destroying the structure of the nuclear protein.

Concentration Related to Time Needed for Virucidal Action
HOCl has been shown to inactivate a variety of viruses including coronaviruses in less than 1 minute. At a concentration of 200 ppm, HOCl is effective in decontaminating inert surfaces carrying noroviruses and other enteric viruses in a 1-minute contact time. When diluted 10 times, HOCl solutions at 20 ppm is still effective in decontaminating environmental surfaces carrying viruses in a 10-minute contact time.

Mouth Rinse
If HOCl is used as a mouth rinse, one must assume that a portion of the rinse will be swallowed.
No abnormal or any symptoms are found.

Ophthalmology
HOCl is used in the treatment of blepharitis by reducing the bacterial load on the surface of the skin.

Biofilm
HOCl significantly reduces bacteria on toothbrushes; it is effective as a mouthwash and for toothbrush disinfection.

Wound Care
In a clinical study on intraperitoneal wound care, patients have undergone lavage of the peritoneal cavity with 100-ppm HOCl and washing of the wound with 200 ppm. No abnormal effects were found.  Postoperative closure failure occurred in more than 80% of patients in the saline solution group; however, only 25% of those in the HOCl group.  Thus, HOCl has been shown to be an effective agent in reducing wound bacterial counts in open wounds.

Hand Sanitizing
Hand antiseptics are alcohol-based or non–alcohol-based containing antibiotic compounds. HOCl specifically is used for hand sanitisers is effective at 100- to 200-ppm strengths.

Surface Application
A study looked at disinfecting outpatient surgical centres using HOCl.  After cleaning, the rooms in the HOCl cleaning and disinfection study had significantly lower bacterial counts than the rooms that underwent standard cleaning and disinfection.

Apply HOCl by spray or atomizer
In addition to the use of HOCl in the form of wet wipes for disinfection, the use of HOCl vapour through a nebulizer is an economical way to disinfect large operating rooms or suites.

The atomization process will change the physical and chemical properties of the disinfectant, making it thinner and more alkaline.

The ability of the nebulizer to produce smaller particles may help the solution molecules to stay in the air longer because of their lower settling velocity.

This can increase the chance that the solution will come into contact with pathogens and inactivate them, as a result, will kill more bacteria.

Source from:
National Center for Biotechnology Information
(USA)  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315945/

TS-310 Specifications :

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